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Flexibility of the Adenovirus Fiber Is Required for Efficient Receptor Interaction

The adenovirus (Ad) fiber protein mediates Ad binding to the coxsackievirus and Ad receptor (CAR) and is thus a major determinant of viral tropism. The fiber contains three domains: an N-terminal tail that anchors the fiber to the viral capsid, a central shaft region of variable length and flexibili...

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Detalhes bibliográficos
Main Authors: Wu, Eugene, Pache, Lars, Von Seggern, Dan J., Mullen, Tina-Marie, Mikyas, Yeshi, Stewart, Phoebe L., Nemerow, Glen R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC164825/
https://ncbi.nlm.nih.gov/pubmed/12805421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.13.7225-7235.2003
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