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Role for the Fission Yeast RecQ Helicase in DNA Repair in G(2)

Members of the RecQ helicase subfamily are mutated in several human genomic instability syndromes, such as Bloom, Werner, and Rothmund-Thomson syndromes. We show that Rqh1, the single Schizosaccharomyces pombe homologue, is a 3′-to-5′ helicase and exists with Top3 in a high-molecular-weight complex....

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Detalles Bibliográficos
Main Authors: Laursen, Louise V., Ampatzidou, Eleni, Andersen, Anni H., Murray, Johanne M.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2003
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC164774/
https://ncbi.nlm.nih.gov/pubmed/12724426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.10.3692-3705.2003
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