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Role for the Fission Yeast RecQ Helicase in DNA Repair in G(2)
Members of the RecQ helicase subfamily are mutated in several human genomic instability syndromes, such as Bloom, Werner, and Rothmund-Thomson syndromes. We show that Rqh1, the single Schizosaccharomyces pombe homologue, is a 3′-to-5′ helicase and exists with Top3 in a high-molecular-weight complex....
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC164774/ https://ncbi.nlm.nih.gov/pubmed/12724426 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.10.3692-3705.2003 |
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