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Replication of the Chicken β-Globin Locus: Early-Firing Origins at the 5′ HS4 Insulator and the ρ- and β(A)-Globin Genes Show Opposite Epigenetic Modifications

Chromatin structure is believed to exert a strong effect on replication origin function. We have studied the replication of the chicken β-globin locus, whose chromatin structure has been extensively characterized. This locus is delimited by hypersensitive sites (HSs) that mark the position of insula...

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Detalhes bibliográficos
Main Authors: Prioleau, Marie-Noëlle, Gendron, Marie-Claude, Hyrien, Olivier
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC164771/
https://ncbi.nlm.nih.gov/pubmed/12724412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.10.3536-3549.2003
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