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The U1 snRNP Base Pairs with the 5′ Splice Site within a Penta-snRNP Complex

Recognition of the 5′ splice site is an important step in mRNA splicing. To examine whether U1 approaches the 5′ splice site as a solitary snRNP or as part of a multi-snRNP complex, we used a simplified in vitro system in which a short RNA containing the 5′ splice site sequence served as a substrate...

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Hlavní autoři: Malca, Hadar, Shomron, Noam, Ast, Gil
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2003
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC164765/
https://ncbi.nlm.nih.gov/pubmed/12724403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.10.3442-3455.2003
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