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FAP-1 Association with Fas (Apo-1) Inhibits Fas Expression on the Cell Surface

As revealed by intracellular pools of nonactive Fas (Apo-1), export of Fas to the cell surface is often impaired in human tumors, thereby inactivating Fas ligand-mediated apoptosis. Here, we demonstrate that association with Fas-associated phosphatase 1 (FAP-1) attenuates Fas export to the cell surf...

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Bibliografiske detaljer
Udgivet i:Mol Cell Biol
Principais autores: Ivanov, Vladimir N., Bergami, Pablo Lopez, Maulit, Gabriel, Sato, Taka-Aki, Sassoon, David, Ronai, Ze'ev
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2003
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC164761/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12724420/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.10.3623-3635.2003
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