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FAP-1 Association with Fas (Apo-1) Inhibits Fas Expression on the Cell Surface
As revealed by intracellular pools of nonactive Fas (Apo-1), export of Fas to the cell surface is often impaired in human tumors, thereby inactivating Fas ligand-mediated apoptosis. Here, we demonstrate that association with Fas-associated phosphatase 1 (FAP-1) attenuates Fas export to the cell surf...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology
2003
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC164761/ https://ncbi.nlm.nih.gov/pubmed/12724420 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.10.3623-3635.2003 |
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