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Structural determinant of TRPV1 desensitization interacts with calmodulin

The capsaicin receptor, TRPV1 (VR1), is a sensory neuron-specific ion channel that serves as a polymodal detector of pain-producing chemical and physical stimuli. Extracellular Ca(2+)-dependent desensitization of TRPV1 observed in patch–clamp experiments when using both heterologous expression syste...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Numazaki, Mitsuko, Tominaga, Tomoko, Takeuchi, Kumiko, Murayama, Namie, Toyooka, Hidenori, Tominaga, Makoto
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2003
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC164702/
https://ncbi.nlm.nih.gov/pubmed/12808128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1337252100
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