Mifepristone (RU486) protects Purkinje cells from cell death in organotypic slice cultures of postnatal rat and mouse cerebellum

Mifepristone (RU486), which binds with high affinity to both progesterone and glucocorticosteroid receptors (PR and GR), is well known for its use in the termination of unwanted pregnancy, but other activities including neuroprotection have been suggested. Cerebellar organotypic cultures from 3 to 7...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Ghoumari, A. M., Dusart, I., El-Etr, M., Tronche, F., Sotelo, C., Schumacher, M., Baulieu, E.-E.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2003
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC164694/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12810951/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.1332667100
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