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Stepwise cytoskeletal polarization as a series of checkpoints in innate but not adaptive cytolytic killing

Cytolytic killing is a major effector mechanism in the elimination of virally infected and tumor cells. The innate cytolytic effectors, natural killer (NK) cells, and the adaptive effectors, cytotoxic T cells (CTL), despite differential immune recognition, both use the same lytic mechanism, cytolyti...

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Detalhes bibliográficos
Main Authors: Wülfing, Christoph, Purtic, Bozidar, Klem, Jennifer, Schatzle, John D.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC164662/
https://ncbi.nlm.nih.gov/pubmed/12802007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1336920100
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