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A multistep mechanism for the activation of rearrangement in the immune system

Rearrangement of immune receptor loci is a developmentally controlled process that takes place exclusively in lymphoid cells. We have used a stable transfection system in pre-B cells to show that DNA methylation brings about histone underacetylation, histone H3(K9) methylation, DNaseI resistance, an...

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Autors principals: Ji, Yanhong, Zhang, Jianmin, Lee, Alfred Ian, Cedar, Howard, Bergman, Yehudit
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC164625/
https://ncbi.nlm.nih.gov/pubmed/12802019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0932635100
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