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Human acetyl-CoA carboxylase 1 gene: Presence of three promoters and heterogeneity at the 5′-untranslated mRNA region
Acetyl-CoA carboxylase 1 (ACC1) catalyzes the formation of malonyl-CoA, the C(2) donor for de novo synthesis of long-chain fatty acids. We have identified 64 exons, including 7 alternatively spliced minor exons (1A, 1B, 1C, 3, 5A′, 5A, and 5B) in human ACC1 gene (≈330 kb). The gene is regulated by t...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC164618/ https://ncbi.nlm.nih.gov/pubmed/12810950 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1332670100 |
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