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Human acetyl-CoA carboxylase 1 gene: Presence of three promoters and heterogeneity at the 5′-untranslated mRNA region

Acetyl-CoA carboxylase 1 (ACC1) catalyzes the formation of malonyl-CoA, the C(2) donor for de novo synthesis of long-chain fatty acids. We have identified 64 exons, including 7 alternatively spliced minor exons (1A, 1B, 1C, 3, 5A′, 5A, and 5B) in human ACC1 gene (≈330 kb). The gene is regulated by t...

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Bibliografski detalji
Glavni autori: Mao, Jianqiang, Chirala, Subrahmanyam S., Wakil, Salih J.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2003
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC164618/
https://ncbi.nlm.nih.gov/pubmed/12810950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1332670100
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