A lupus-like syndrome develops in mice lacking the Ro 60-kDa protein, a major lupus autoantigen

Antibodies against a conserved RNA-binding protein, the Ro 60-kDa autoantigen, occur in 24–60% of all patients with systemic lupus erythematosus. Anti-Ro antibodies are correlated with photosensitivity and cutaneous lesions in these patients and with neonatal lupus, a syndrome in which mothers with...

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Autors principals: Xue, Dahai, Shi, Hong, Smith, James D., Chen, Xinguo, Noe, Dennis A., Cedervall, Tommy, Yang, Derek D., Eynon, Elizabeth, Brash, Douglas E., Kashgarian, Michael, Flavell, Richard A., Wolin, Sandra L.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2003
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC164616/
https://ncbi.nlm.nih.gov/pubmed/12788971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0832411100
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