Validation of the hexose transporter of Plasmodium falciparum as a novel drug target
Chemotherapy of malaria parasites is limited by established drug resistance and lack of novel targets. Intraerythrocytic stages of Plasmodium falciparum are wholly dependent on host glucose for energy. Glucose uptake is mediated by a parasite-encoded facilitative hexose transporter (PfHT). We report...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2003
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC164611/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12792024/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.1330865100 |
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