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Validation of the hexose transporter of Plasmodium falciparum as a novel drug target

Chemotherapy of malaria parasites is limited by established drug resistance and lack of novel targets. Intraerythrocytic stages of Plasmodium falciparum are wholly dependent on host glucose for energy. Glucose uptake is mediated by a parasite-encoded facilitative hexose transporter (PfHT). We report...

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Autori principali: Joët, Thierry, Eckstein-Ludwig, Ursula, Morin, Christophe, Krishna, Sanjeev
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC164611/
https://ncbi.nlm.nih.gov/pubmed/12792024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1330865100
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