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Validation of the hexose transporter of Plasmodium falciparum as a novel drug target

Chemotherapy of malaria parasites is limited by established drug resistance and lack of novel targets. Intraerythrocytic stages of Plasmodium falciparum are wholly dependent on host glucose for energy. Glucose uptake is mediated by a parasite-encoded facilitative hexose transporter (PfHT). We report...

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Detalhes bibliográficos
Main Authors: Joët, Thierry, Eckstein-Ludwig, Ursula, Morin, Christophe, Krishna, Sanjeev
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC164611/
https://ncbi.nlm.nih.gov/pubmed/12792024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1330865100
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