Carbohydrate-dependent signaling from the phosphatidylglucoside-based microdomain induces granulocytic differentiation of HL60 cells

Glycosphingolipids form glycosphingolipid signaling microdomains. Here, we report an unrecognized type of phosphatidylglucoside (PhGlc)-based lipid microdomain in HL60 cells. Treatment of cells with rGL-7, which preferentially reacts with PhGlc, induced differentiation of HL60 cells. This was manife...

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Detalhes bibliográficos
Main Authors: Nagatsuka, Yasuko, Hara-Yokoyama, Miki, Kasama, Takeshi, Takekoshi, Masataka, Maeda, Fumiko, Ihara, Seiji, Fujiwara, Shigeyoshi, Ohshima, Eriko, Ishii, Kumiko, Kobayashi, Toshihide, Shimizu, Kazufumi, Hirabayashi, Yoshio
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2003
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC164607/
https://ncbi.nlm.nih.gov/pubmed/12802014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1232503100
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