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Inhibition of p53-induced apoptosis without affecting expression of p53-regulated genes

Using DNA microarray and clustering of expressed genes we have analyzed the mechanism of inhibition of wild-type p53-induced apoptosis by the cytokine interleukin 6 (IL-6) and the calcium mobilizer thapsigargin (TG). Clustering analysis of 1,786 genes, the expression level of which changed after act...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Lotem, Joseph, Gal, Hilah, Kama, Rachel, Amariglio, Ninette, Rechavi, Gideon, Domany, Eytan, Sachs, Leo, Givol, David
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2003
Schlagworte:
Biological Sciences
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC164513/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12743373/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.1031695100
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