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Instability of GGL domain-containing RGS proteins in mice lacking the G protein β-subunit Gβ5

RGS (regulator of G protein signaling) proteins containing the G protein γ-like (GGL) domain (RGS6, RGS7, RGS9, and RGS11) interact with the fifth member of the G protein β-subunit family, Gβ5. This interaction is necessary for the stability of both the RGS protein and for Gβ5. Consistent with this...

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Main Authors: Chen, Ching-Kang, Eversole-Cire, Pamela, Zhang, Haikun, Mancino, Valeria, Chen, Yu-Jiun, He, Wei, Wensel, Theodore G., Simon, Melvin I.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2003
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC164494/
https://ncbi.nlm.nih.gov/pubmed/12738888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0631825100
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