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Abnormal phagocytosis by retinal pigmented epithelium that lacks myosin VIIa, the Usher syndrome 1B protein

Mutations in the myosin VIIa gene (MYO7A) cause Usher syndrome type 1B (USH1B), a major type of the deaf-blind disorder, Usher syndrome. We have studied mutant phenotypes in the retinas of Myo7a mutant mice (shaker1), with the aim of elucidating the role(s) of myosin VIIa in the retina and what migh...

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Auteurs principaux: Gibbs, Daniel, Kitamoto, Junko, Williams, David S.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2003
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC164472/
https://ncbi.nlm.nih.gov/pubmed/12743369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1130432100
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