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Exo1: A new chemical inhibitor of the exocytic pathway

A phenotypic screen was used to search for drug-like molecules that can interfere with specific steps in membrane traffic. 2-(4-Fluorobenzoylamino)-benzoic acid methyl ester (Exo1), identified in this screen, induces a rapid collapse of the Golgi to the endoplasmic reticulum, thus acutely inhibiting...

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Detalhes bibliográficos
Main Authors: Feng, Yan, Yu, Sidney, Lasell, Troy K. R., Jadhav, Ashutosh P., Macia, Eric, Chardin, Pierre, Melancon, Paul, Roth, Michael, Mitchison, Timothy, Kirchhausen, Tomas
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC164470/
https://ncbi.nlm.nih.gov/pubmed/12738886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0631766100
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