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Chloride, not sodium, stimulates expression of the γ subunit of Na/K-ATPase and activates JNK in response to hypertonicity in mouse IMCD3 cells

Hypertonicity induced by NaCl, but not by urea or mannitol, up-regulates expression of the γ subunit of Na/K-ATPase in cells of the murine inner medullary collecting duct line (IMCD3) by activation of the Jun kinase 2 (JNK2) pathways. We examined the ionic mediators of the osmosensitive response. An...

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Detalhes bibliográficos
Main Authors: Capasso, Juan M., Rivard, Christopher J., Enomoto, Laura M., Berl, Tomas
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC164463/
https://ncbi.nlm.nih.gov/pubmed/12746499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1130871100
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