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Paradoxical activation of the sodium chloride cotransporter (NCC) without hypertension in kidney deficient in a regulatory subunit of Na,K‐ATPase, FXYD2

Na,K‐ATPase generates the driving force for sodium reabsorption in the kidney. Na,K‐ATPase functional properties are regulated by small proteins belonging to the FXYD family. In kidney FXYD2 is the most abundant: it is an inhibitory subunit expressed in almost every nephron segment. Its absence shou...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Physiol Rep
Egile Nagusiak: Arystarkhova, Elena, Ralph, Donna L., Liu, Yi Bessie, Bouley, Richard, McDonough, Alicia A., Sweadner, Kathleen J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Wiley Periodicals, Inc. 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4332208/
https://ncbi.nlm.nih.gov/pubmed/25472608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12226
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