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How the BfiI restriction enzyme uses one active site to cut two DNA strands

Unlike other restriction enzymes, BfiI functions without metal ions. It recognizes an asymmetric DNA sequence, 5′-ACTGGG-3′, and cuts top and bottom strands at fixed positions downstream of this sequence. Many restriction enzymes are dimers of identical subunits, with one active site for each DNA st...

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Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Sasnauskas, Giedrius, Halford, Stephen E., Siksnys, Virginijus
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2003
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC164460/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12750473/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.1131003100
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