Genomewide view of gene silencing by small interfering RNAs

RNA interference (RNAi) is an evolutionarily conserved mechanism in plant and animal cells that directs the degradation of messenger RNAs homologous to short double-stranded RNAs termed small interfering RNA (siRNA). The ability of siRNA to direct gene silencing in mammalian cells has raised the pos...

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Bibliographic Details
Main Authors: Chi, Jen-Tsan, Chang, Howard Y., Wang, Nancy N., Chang, Dustin S., Dunphy, Nina, Brown, Patrick O.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2003
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC164448/
https://ncbi.nlm.nih.gov/pubmed/12730368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1037853100
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