BAFF selectively enhances the survival of plasmablasts generated from human memory B cells

The generation of Ig-secreting cells (ISCs) from memory B cells requires interactions between antigen-specific (Ag-specific) B cells, T cells, and dendritic cells. This process must be strictly regulated to ensure sufficient humoral immunity while avoiding production of pathogenic autoantibodies. BA...

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Autores principales: Avery, Danielle T., Kalled, Susan L., Ellyard, Julia I., Ambrose, Christine, Bixler, Sarah A., Thien, Marilyn, Brink, Robert, Mackay, Fabienne, Hodgkin, Philip D., Tangye, Stuart G.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2003
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC164292/
https://ncbi.nlm.nih.gov/pubmed/12865416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200318025
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