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Fungicidal mechanism of action of D0870 against Cryptococcus neoformans under acidic conditions.

The fungicidal mechanism of the triazole D0870 against Cryptococcus neoformans under acidic conditions was investigated. D0870 reduced the intracellular K+ content of C. neoformans at pH 4 to about half the value at pH 7 after 12 h of incubation. The 50% inhibitory concentrations of D0870 for ergost...

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Dades bibliogràfiques
Publicat a:Antimicrob Agents Chemother
Autors principals: Yamada, H, Watanabe, T, Kato, K, Mochizuki, H
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 1997
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC164193/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9420043/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.41.12.2710
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