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Fungicidal mechanism of action of D0870 against Cryptococcus neoformans under acidic conditions.

The fungicidal mechanism of the triazole D0870 against Cryptococcus neoformans under acidic conditions was investigated. D0870 reduced the intracellular K+ content of C. neoformans at pH 4 to about half the value at pH 7 after 12 h of incubation. The 50% inhibitory concentrations of D0870 for ergost...

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Publicado en:Antimicrob Agents Chemother
Autores principales: Yamada, H, Watanabe, T, Kato, K, Mochizuki, H
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 1997
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC164193/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9420043/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.41.12.2710
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