CD8 T Cells Control Cytomegalovirus Latency by Epitope-Specific Sensing of Transcriptional Reactivation

During murine cytomegalovirus (mCMV) latency in the lungs, most of the viral genomes are transcriptionally silent at the major immediate-early locus, but rare and stochastic episodes of desilencing lead to the expression of IE1 transcripts. This low-frequency but perpetual expression is accompanied...

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Bibliografiska uppgifter
Huvudupphovsmän: Simon, Christian O., Holtappels, Rafaela, Tervo, Hanna-Mari, Böhm, Verena, Däubner, Torsten, Oehrlein-Karpi, Silke A., Kühnapfel, Birgit, Renzaho, Angélique, Strand, Dennis, Podlech, Jürgen, Reddehase, Matthias J., Grzimek, Natascha K. A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2006
Ämnen:
Virus-Cell Interactions
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1641801/
https://ncbi.nlm.nih.gov/pubmed/16928768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01248-06
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