Nef Alleles from Human Immunodeficiency Virus Type 1-Infected Long-Term-Nonprogressor Hemophiliacs with or without Late Disease Progression Are Defective in Enhancing Virus Replication and CD4 Down-Regulation

Infection with human immunodeficiency virus (HIV)-encoding defective nef variants may contribute to a relatively benign course of disease in a minority of long-term nonprogressors (LTNP). We have examined the functions of nef alleles from six individuals belonging to the same cohort of hemophiliacs...

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Detalhes bibliográficos
Main Authors: Crotti, Andrea, Neri, Francesca, Corti, Davide, Ghezzi, Silvia, Heltai, Silvia, Baur, Andreas, Poli, Guido, Santagostino, Elena, Vicenzi, Elisa
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1641799/
https://ncbi.nlm.nih.gov/pubmed/16943296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02621-05
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