Construction of a Severe Acute Respiratory Syndrome Coronavirus Infectious cDNA Clone and a Replicon To Study Coronavirus RNA Synthesis

The engineering of a full-length infectious cDNA clone and a functional replicon of the severe acute respiratory syndrome coronavirus (SARS-CoV) Urbani strain as bacterial artificial chromosomes (BACs) is described in this study. In this system, the viral RNA was expressed in the cell nucleus under...

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Detalhes bibliográficos
Main Authors: Almazán, Fernando, DeDiego, Marta L., Galán, Carmen, Escors, David, Álvarez, Enrique, Ortego, Javier, Sola, Isabel, Zuñiga, Sonia, Alonso, Sara, Moreno, Jose L., Nogales, Aitor, Capiscol, Carmen, Enjuanes, Luis
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1641757/
https://ncbi.nlm.nih.gov/pubmed/16928748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00385-06
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