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Effectiveness of quinolone antibiotics in modulating the effects of antifungal drugs.

Quinolone antibacterial drugs inhibit DNA gyrase, a type 2 topoisomerase. Since topoisomerases are present in eukaryotic cells, it was of interest to evaluate the antifungal activities of two clinically available quinolones, ciprofloxacin and trovafloxacin, alone and in combination with amphotericin...

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Detalhes bibliográficos
Main Authors: Sugar, A M, Liu, X P, Chen, R J
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC164154/
https://ncbi.nlm.nih.gov/pubmed/9371359
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