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Comparative metabolism of the antiviral dimer 3'-azido-3'-deoxythymidine-P-2',3'-dideoxyinosine and the monomers zidovudine and didanosine by rat, monkey, and human hepatocytes.
AZT-P-ddI is an antiviral heterodimer composed of one molecule of 3'-azido-3'-deoxythymidine (AZT) and one molecule of 2',3'-dideoxyinosine (ddI) linked through their 5' positions by a phosphate bond. The metabolic fate of the dimer was studied with isolated rat, monkey, and...
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Huvudupphovsmän: | , , , , , , , |
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Materialtyp: | Artigo |
Språk: | Inglês |
Publicerad: |
1997
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Ämnen: | |
Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC164152/ https://ncbi.nlm.nih.gov/pubmed/9371357 |
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