Exposure-response relationships for saquinavir, zidovudine, and zalcitabine in combination therapy.

The relationship of CD4+ cell response, level of RNA in plasma, and quantitative peripheral blood mononuclear cell (PBMC) titer to apparent drug exposure was investigated by using data from AIDS Clinical Trial Group protocol 229, a multicenter randomized study. Patients received either saquinavir, z...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Vanhove, G F, Gries, J M, Verotta, D, Sheiner, L B, Coombs, R, Collier, A C, Blaschke, T F
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1997
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC164141/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9371346/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.41.11.2433
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