Exposure-response relationships for saquinavir, zidovudine, and zalcitabine in combination therapy.

The relationship of CD4+ cell response, level of RNA in plasma, and quantitative peripheral blood mononuclear cell (PBMC) titer to apparent drug exposure was investigated by using data from AIDS Clinical Trial Group protocol 229, a multicenter randomized study. Patients received either saquinavir, z...

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Autores principales: Vanhove, G F, Gries, J M, Verotta, D, Sheiner, L B, Coombs, R, Collier, A C, Blaschke, T F
Formato: Artigo
Lenguaje:Inglês
Publicado: 1997
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC164141/
https://ncbi.nlm.nih.gov/pubmed/9371346
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