Pharmacodynamics and bactericidal activity of ceftriaxone therapy in experimental cephalosporin-resistant pneumococcal meningitis.

Adequate concentrations of beta-lactam antibiotics in cerebrospinal fluid (CSF) are difficult to achieve for meningitis caused by drug-resistant Streptococcus pneumoniae. Ceftriaxone in dosages of 150 or 400 mg/kg of body weight per day, given in one or two doses, was used for the treatment of exper...

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Vydáno v:	Antimicrob Agents Chemother
Hlavní autoři:	Lutsar, I, Ahmed, A, Friedland, I R, Trujillo, M, Wubbel, L, Olsen, K, McCracken, G H
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 1997
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC164137/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9371342/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.41.11.2414
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