Pharmacodynamics of Gatifloxacin in Cerebrospinal Fluid in Experimental Cephalosporin-Resistant Pneumococcal Meningitis

The purpose of this study was to evaluate the cerebrospinal fluid (CSF) pharmacodynamics of a new fluoroquinolone, gatifloxacin (AM-1155), in experimental pneumococcal meningitis. The penetration of gatifloxacin into CSF, calculated as the percentage of the area under the concentration-time curve (A...

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Bibliografiska uppgifter
Huvudupphovsmän: Lutsar, Irja, Friedland, Ian R., Wubbel, Loretta, McCoig, Cynthia C., Jafri, Hasan S., Ng, Winston, Ghaffar, Faryal, McCracken, George H.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 1998
Ämnen:
Experimental Therapeutics
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC105913/
https://ncbi.nlm.nih.gov/pubmed/9756771
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