Pharmacodynamics of Gatifloxacin in Cerebrospinal Fluid in Experimental Cephalosporin-Resistant Pneumococcal Meningitis

The purpose of this study was to evaluate the cerebrospinal fluid (CSF) pharmacodynamics of a new fluoroquinolone, gatifloxacin (AM-1155), in experimental pneumococcal meningitis. The penetration of gatifloxacin into CSF, calculated as the percentage of the area under the concentration-time curve (A...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Lutsar, Irja, Friedland, Ian R., Wubbel, Loretta, McCoig, Cynthia C., Jafri, Hasan S., Ng, Winston, Ghaffar, Faryal, McCracken, George H.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1998
Schlagworte:	Experimental Therapeutics
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105913/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9756771/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.10.2650
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