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Absorption of ofloxacin isomers in the rat small intestine.

Ofloxacin, a chiral fluoroquinolone, possesses two optical isomers. The antibacterial activity of S-(-)-ofloxacin is 8 to 128 times higher than that of R-(+)-ofloxacin. In the rat, a saturable absorption process has been described for racemic ofloxacin. In the present study we investigated the mecha...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Rabbaa, L, Dautrey, S, Colas-Linhart, N, Carbon, C, Farinotti, R
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC164106/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9333061/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.41.10.2274
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