In vivo efficacies of 5'-methylthioadenosine analogs as trypanocides.
5'-Deoxy-5'-(methylthio)adenosine (MTA), a key by-product of polyamine biosynthesis, is cleaved by MTA phosphorylase and is salvaged as adenine and, through conversion of the ribose moiety, methionine. An analog of MTA, 5'-deoxy-5'-(hydroxyethylthio)adenosine (HETA), is a substrate for trypanosome M...
Guardat en:
| Publicat a: | Antimicrob Agents Chemother |
|---|---|
| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology (ASM)
1997
|
| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC164078/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9333033/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.41.10.2108 |
| Etiquetes: |
Sense etiquetes, Sigues el primer a etiquetar aquest registre!
|