Pharmacokinetic and pharmacodynamic models of the antistaphylococcal effects of meropenem and cloxacillin in vitro and in experimental infection.

The efficacies of meropenem (MPM) and cloxacillin (CLC) against two Staphylococcus aureus strains were established in vitro. A pharmacodynamic model equation, based on the concept that the killing rate depends on concentration and time, was fitted to the numbers of CFU. The parameters of the equatio...

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Yayımlandı:	Antimicrob Agents Chemother
Asıl Yazarlar:	Mattie, H, Zhang, L C, van Strijen, E, Sekh, B R, Douwes-Idema, A E
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	American Society for Microbiology (ASM) 1997
Konular:	Research Article
Online Erişim:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC164074/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9333029/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.41.10.2083
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