Pharmacokinetic and pharmacodynamic models of the antistaphylococcal effects of meropenem and cloxacillin in vitro and in experimental infection.

The efficacies of meropenem (MPM) and cloxacillin (CLC) against two Staphylococcus aureus strains were established in vitro. A pharmacodynamic model equation, based on the concept that the killing rate depends on concentration and time, was fitted to the numbers of CFU. The parameters of the equatio...

ver descrição completa

Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Mattie, H, Zhang, L C, van Strijen, E, Sekh, B R, Douwes-Idema, A E
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1997
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC164074/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9333029/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.41.10.2083
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!