Pharmacokinetic interaction between itraconazole and ceftriaxone in Yucatan miniature pigs.

Since ceftriaxone and itraconazole are highly protein bound, are excreted via a biliary pathway, and are in vitro modulators of the efflux pump P glycoprotein, a pharmacokinetic interaction between these antimicrobial agents can be hypothesized. Therefore, we evaluated the pharmacokinetics of itraco...

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Hlavní autoři: Cavalier, A, Levêque, D, Peter, J D, Salmon, J, Elkhaïli, H, Salmon, Y, Nobelis, P, Geisert, J, Monteil, H, Jehl, F
Médium: Artigo
Jazyk:Inglês
Vydáno: 1997
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC164060/
https://ncbi.nlm.nih.gov/pubmed/9303409
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