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Pharmacokinetic interaction between itraconazole and ceftriaxone in Yucatan miniature pigs.

Since ceftriaxone and itraconazole are highly protein bound, are excreted via a biliary pathway, and are in vitro modulators of the efflux pump P glycoprotein, a pharmacokinetic interaction between these antimicrobial agents can be hypothesized. Therefore, we evaluated the pharmacokinetics of itraco...

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Publicado en:Antimicrob Agents Chemother
Autores principales: Cavalier, A, Levêque, D, Peter, J D, Salmon, J, Elkhaïli, H, Salmon, Y, Nobelis, P, Geisert, J, Monteil, H, Jehl, F
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 1997
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC164060/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9303409/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.41.9.2029
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