Construction and characterization of an OHIO-1 beta-lactamase bearing Met69Ile and Gly238Ser mutations.

Amino acid changes that influence activity and resistance to beta-lactams and beta-lactamase inhibitors were explored by constructing the Gly238Ser and Met69Ile-Gly238Ser mutants of the OHIO-1 beta-lactamase, a class A enzyme of the SHV family. The Km values of cefotaxime and ceftazidime for OHIO-1...

全面介紹

書目詳細資料

發表在:	Antimicrob Agents Chemother
Principais autores:	Bonomo, R A, Knox, J R, Rudin, S D, Shlaes, D M
格式:	Artigo
語言:	Inglês
出版:	American Society for Microbiology (ASM) 1997
主題:	Research Article
在線閱讀:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC164040/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9303389/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.41.9.1940
標簽:	添加標簽 沒有標簽, 成為第一個標記此記錄!