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Cerebrospinal fluid bactericidal activity against cephalosporin-resistant Streptococcus pneumoniae in children with meningitis treated with high-dosage cefotaxime.

We determined cefotaxime and desacetyl-cefotaxime concentrations in children with bacterial meningitis receiving high-dose cefotaxime (300 mg/kg of body weight/day) and concomitant dexamethasone therapy. The median peak cerebrospinal fluid cefotaxime and desacetyl-cefotaxime concentrations were 4.7...

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Библиографические подробности
Опубликовано в::Antimicrob Agents Chemother
Главные авторы: Friedland, I R, Klugman, K P
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology (ASM) 1997
Предметы:
Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC164030/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9303379/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.41.9.1888
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