Enhancement of nitric oxide synthesis by macrophages represents an additional mechanism of action for amphotericin B.

Amphotericin B (AmB) enhanced nitrite synthesis by murine macrophage-like J774.16 cells in a dose-dependent fashion. This effect was retained in the presence of Cryptococcus neoformans capsular polysaccharide, a known virulence factor. AmB and anticapsular antibody increased nitrite synergistically....

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Shranjeno v:
Bibliografske podrobnosti
Main Authors: Mozaffarian, N, Berman, J W, Casadevall, A
Format: Artigo
Jezik:Inglês
Izdano: 1997
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC164015/
https://ncbi.nlm.nih.gov/pubmed/9257771
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