Enhancement of nitric oxide synthesis by macrophages represents an additional mechanism of action for amphotericin B.
Amphotericin B (AmB) enhanced nitrite synthesis by murine macrophage-like J774.16 cells in a dose-dependent fashion. This effect was retained in the presence of Cryptococcus neoformans capsular polysaccharide, a known virulence factor. AmB and anticapsular antibody increased nitrite synergistically....
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| Publicado no: | Antimicrob Agents Chemother |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
1997
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC164015/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9257771/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.41.8.1825 |
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