Treatment of murine disseminated candidiasis with L-743,872.

L-743,872 (M991), which is a pneumocandin derivative, was evaluated in a mouse model of disseminated candidiasis caused by a fluconazole-resistant isolate of Candida albicans. In immunocompetent mice M991 prolonged survival at doses as low as 0.0125 mg/kg of body weight per day. In neutropenic mice...

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Publicado en:	Antimicrob Agents Chemother
Autores principales:	Graybill, J R, Najvar, L K, Luther, M F, Fothergill, A W
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 1997
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC164003/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9257759/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.41.8.1775
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