The postantibiotic effect of imipenem: relationship with drug concentration, duration of exposure, and MIC.

The postantibiotic effect (PAE) of imipenem against Escherichia coli was measured at a wide variety of drug concentrations and times of exposure. We observed that the area under the concentration-time curve of drug exposure (AUC), the product of time of exposure and concentration of drug, is a much...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Munckhof, W J, Olden, D, Turnidge, J D
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1997
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163995/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9257751/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.41.8.1735
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