Inducible expression of human hepatitis B virus (HBV) in stably transfected hepatoblastoma cells: a novel system for screening potential inhibitors of HBV replication.

We report the development and isolation of a cell line, termed HepAD38, that replicates human hepatitis B virus (HBV) under conditions that can be regulated with tetracycline. In the presence of the antibiotic, this cell line is free of virus due to the repression of pregenomic (pg) RNA synthesis. U...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Ladner, S K, Otto, M J, Barker, C S, Zaifert, K, Wang, G H, Guo, J T, Seeger, C, King, R W
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1997
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163991/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9257747/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.41.8.1715
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